ABSTRACT
Sebaceous hyperplasia usually presents as solitary or multiple, small, yellowish papules on the face, particularly on the forehead. It occurs most commonly in middle-aged individuals and rarely in early adult life. It has also been reported in the vulva, penis, and areola. Histological examination reveals a single greatly enlarged sebaceous gland composed of numerous lobules grouped around a centrally located, wide sebaceous duct. We report a case of a 26-year-old man with sebaceous hyperplasia in the ventral surface of the distal penile shaft, an unusual site.
Subject(s)
Adult , Humans , Male , Forehead , Hyperplasia , Penis , Sebaceous Glands , VulvaABSTRACT
Disseminated superficial porokeratosis (DSP) is a specific disorder of keratinization. Genetic studies show that DSP is an autosomal dominant trait. Clinically, the lesions show a sharply demarcated and hyperkeratotic plaque with central atrophy. The lesions appear mainly in the extremities and generally develop with bilateral symmetry. Unusual cases of DSP accompanied by severe pruritus have been reported as "eruptive pruritic papular porokeratosis" or "inflammatory DSP." Histopathologically, inflammatory DSP is characterized by the presence of cornoid lamella with a dense infiltration of eosinophils and lymphocytes in the perivascular area of the upper dermis. Here we report a case of inflammatory DSP in a 84-year-old man with colon cancer who presented with multiple hyperpigmented atrophic macules.
Subject(s)
Aged, 80 and over , Humans , Atrophy , Colon , Colonic Neoplasms , Dermis , Eosinophils , Extremities , Keratins , Lymphocytes , Porokeratosis , PruritusABSTRACT
Disseminated superficial porokeratosis (DSP) is a specific disorder of keratinization. Genetic studies show that DSP is an autosomal dominant trait. Clinically, the lesions show a sharply demarcated and hyperkeratotic plaque with central atrophy. The lesions appear mainly in the extremities and generally develop with bilateral symmetry. Unusual cases of DSP accompanied by severe pruritus have been reported as "eruptive pruritic papular porokeratosis" or "inflammatory DSP." Histopathologically, inflammatory DSP is characterized by the presence of cornoid lamella with a dense infiltration of eosinophils and lymphocytes in the perivascular area of the upper dermis. Here we report a case of inflammatory DSP in a 84-year-old man with colon cancer who presented with multiple hyperpigmented atrophic macules.
Subject(s)
Aged, 80 and over , Humans , Atrophy , Colon , Colonic Neoplasms , Dermis , Eosinophils , Extremities , Keratins , Lymphocytes , Porokeratosis , PruritusABSTRACT
Lichen planopilaris is a follicular variant of lichen planus. When it appears on the scalp and is accompanied with hair loss, it is classified into a subtype of cicatrical alopecia. And lichen planopilaris can be classified into classic lichen planopilaris, frontal fibrosing alopecia, Graham-Little syndrome. A 63-year-old man presented with a 3-year history of hair loss on the area of occipital skin and 3-week history of pruritic, confluent, purple-colored, flat-topped papules on the same area with decreased follicular ostium. Histopathological findings showed both characteristics of the cicatricial alopecia and those of lichen planus; Loss of the hair follicles, atrophy of the sebaceous gland and sweat gland, and bandlike inflammatory infiltration on the upper dermis, especially on the perifollicular and interfollicular area.